Friday, September 26, 2025
For decades, scientists puzzled over a genetic anomaly. They just solved it. - The Washington Post
The new study revealed that among translocations studied in three people, these short repeating segments contain the break point where ROBs form. They called these shared, repetitive regions a "recombination hotspot" where the chromosomes line up next to each other and sometimes break and exchange genetic information. They also found a clue as to why one particular chromosome, number 14, is prone to these translocations. It has the repetitive segments, but spelled backward, so when it lines up with another chromosome and a break occurs, the long arms can fuse together...
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